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SUMMARY:Woonggyu Jung\, Ph.D.
DESCRIPTION:Staining-free optical imaging techniques toward digital histopathology \nAbstract \nThe histological optical imaging is a gold standard method to observe the biological tissues\, which follows routine process such as dissection\, embedding\, sectioning\, staining\, visualization and interpretation of specimens. This technique has a long history of development\, and is used ubiquitously in pathology\, despite being highly time and labour-intensive. Advanced optical imaging techniques developed over the last decade have enabled to provide high sensitivity\, high resolution and non-invasive biological information. In particular\, new optical imaging contrast rather than chemical staining has been presented to be utilized in histopathology while showing the strong potential. However\, acquiring high throughput\, large volume tissue anatomy remains a difficult challenge due to the effect of light scattering\, which limits the penetration imaging depth and lateral resolution. Recently\, various optical imaging methods have been introduced to\ncreate volumetric anatomy data of ex vivo tissues using physical tissue sectioning or optical clearing. \nHere\, we introduce novel staining-free and multi-scale imaging modality based on scattering and phase contrast. Optical staining in histopathology could be key technique to build fast feedback of anatomy of tissues or organs due to its simplicity\, efficiency\, robustness\, and high-throughput capabilities. This presentation covers the latest work of large-scale and fast tissue imaging using optical coherence microscopy\, quantitative phase imaging and projection tomography. Specifically\, the talk will highlight comparison study over the conventional method in histopathology and its adaptation with artificial intelligence such as the virtual staining and resolution enhancement. \nBiography \nWoonggyu Jung received his Ph. D. in 2008 from the Department of Biomedical Engineering at the University of California\, Irvine. From 2001 to 2008\, he worked at the Beckman Laser Institute and Medical Clinic at UC Irvine. He also worked at the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign since January 2009. He has joined the faculty of UNIST in 2012\, and currently works as an associate professor of Department of Biomedical Engineering. He is also co-founder and CTO of start-up company\, Conecson which is focused on the futuristic business regarding to mobile-based medical devices. Dr. Jung has a strong research background in optical imaging technologies including optical coherence tomography (OCT)\, quantitative phase microscope (QPM)\, and miniaturized optical imaging probes. His research interest is to develop new optical technologies that address challenges in clinical medicine\, basic biological research and neuroscience. In previous work\, he developed a successful optical platform for in vivo translational research\, and has published more than 60 peer-reviewed journal papers in the field of biophotoics. \nFor more information or to schedule a meeting with the speaker\, please contact Xandra Dvornikova. \nSponsored by the Berns Family Laser and Microbeam Program \nHosted by: Dr. Zhongping Chen
URL:https://bli.uci.edu/event/woonggyu-jung-2/
LOCATION:BLI Library
CATEGORIES:2023 Virtual Seminar Series
ATTACH;FMTTYPE=image/jpeg:https://bli.uci.edu/wp-content/uploads/2020/02/Woonggyu-Jung.jpg
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