BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Beckman Laser Institute - ECPv6.16.3//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Beckman Laser Institute
X-ORIGINAL-URL:https://bli.uci.edu
X-WR-CALDESC:Events for Beckman Laser Institute
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:UTC
BEGIN:STANDARD
TZOFFSETFROM:+0000
TZOFFSETTO:+0000
TZNAME:UTC
DTSTART:20220101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VTIMEZONE
TZID:America/Los_Angeles
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20220313T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20221106T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20230312T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20231105T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20240310T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20241103T090000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=UTC:20230808T150000
DTEND;TZID=UTC:20230808T160000
DTSTAMP:20260914T045421
CREATED:20250325T205417Z
LAST-MODIFIED:20250325T205542Z
UID:32940-1691506800-1691510400@bli.uci.edu
SUMMARY:Woonggyu Jung\, Ph.D.
DESCRIPTION:Staining-free optical imaging techniques toward digital histopathology \nAbstract \nThe histological optical imaging is a gold standard method to observe the biological tissues\, which follows routine process such as dissection\, embedding\, sectioning\, staining\, visualization and interpretation of specimens. This technique has a long history of development\, and is used ubiquitously in pathology\, despite being highly time and labour-intensive. Advanced optical imaging techniques developed over the last decade have enabled to provide high sensitivity\, high resolution and non-invasive biological information. In particular\, new optical imaging contrast rather than chemical staining has been presented to be utilized in histopathology while showing the strong potential. However\, acquiring high throughput\, large volume tissue anatomy remains a difficult challenge due to the effect of light scattering\, which limits the penetration imaging depth and lateral resolution. Recently\, various optical imaging methods have been introduced to\ncreate volumetric anatomy data of ex vivo tissues using physical tissue sectioning or optical clearing. \nHere\, we introduce novel staining-free and multi-scale imaging modality based on scattering and phase contrast. Optical staining in histopathology could be key technique to build fast feedback of anatomy of tissues or organs due to its simplicity\, efficiency\, robustness\, and high-throughput capabilities. This presentation covers the latest work of large-scale and fast tissue imaging using optical coherence microscopy\, quantitative phase imaging and projection tomography. Specifically\, the talk will highlight comparison study over the conventional method in histopathology and its adaptation with artificial intelligence such as the virtual staining and resolution enhancement. \nBiography \nWoonggyu Jung received his Ph. D. in 2008 from the Department of Biomedical Engineering at the University of California\, Irvine. From 2001 to 2008\, he worked at the Beckman Laser Institute and Medical Clinic at UC Irvine. He also worked at the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign since January 2009. He has joined the faculty of UNIST in 2012\, and currently works as an associate professor of Department of Biomedical Engineering. He is also co-founder and CTO of start-up company\, Conecson which is focused on the futuristic business regarding to mobile-based medical devices. Dr. Jung has a strong research background in optical imaging technologies including optical coherence tomography (OCT)\, quantitative phase microscope (QPM)\, and miniaturized optical imaging probes. His research interest is to develop new optical technologies that address challenges in clinical medicine\, basic biological research and neuroscience. In previous work\, he developed a successful optical platform for in vivo translational research\, and has published more than 60 peer-reviewed journal papers in the field of biophotoics. \nFor more information or to schedule a meeting with the speaker\, please contact Xandra Dvornikova. \nSponsored by the Berns Family Laser and Microbeam Program \nHosted by: Dr. Zhongping Chen
URL:https://bli.uci.edu/event/woonggyu-jung-2/
LOCATION:BLI Library
CATEGORIES:2023 Virtual Seminar Series
ATTACH;FMTTYPE=image/jpeg:https://bli.uci.edu/wp-content/uploads/2020/02/Woonggyu-Jung.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231121T120000
DTEND;TZID=America/Los_Angeles:20231121T130000
DTSTAMP:20260914T045421
CREATED:20250325T212039Z
LAST-MODIFIED:20250325T212039Z
UID:32952-1700568000-1700571600@bli.uci.edu
SUMMARY:Xunbin Wei\, Ph.D.
DESCRIPTION:Light Treatment of Alzheimer’s Disease\nAbstract  \nPhotobiomodulation\, by utilizing low-power light in the visible or near-infrared spectrum to trigger biological responses in cells and tissues\, has been considered as a possible therapeutic strategy for Alzheimer’s disease (AD)\, while its specific mechanisms have remained elusive. Here\, we provide evidence that cognitive and memory impairment in an AD mouse model can be ameliorated by 1070-nm light via reducing cerebral β-amyloid (Aβ) burden\, the hallmark of AD. The glial cells\, including microglia and astrocytes\, play important roles in Aβ clearance. Our results show that 1070-nm light pulsed at 10 Hz triggers microglia rather than astrocyte responses in AD mice. The 1070-nm light-induced microglia responses with alteration in morphology and increased colocalization with Aβ are sufficient to reduce Aβ load in AD mice. \nMoreover\, we demonstrate that 1070-nm light pulsed at 10 Hz can reduce perivascular microglia and promote angiogenesis to further improve Aβ clearance. Our study confirms the important roles of microglia and cerebral vessels in the use of 1070-nm light for the treatment of AD mice and provides a framework for developing a novel therapeutic\napproach for AD. \nBiography \nDr. Wei received his bachelor in physics from University of Science and Technology of China\, Hefei. He received his PhD from Department of Physiology and Biophysics\, University of California\, Irvine. Dr. Wei completed his post-doc training at Children’s Hospital\, Harvard Medical School. From 2006-2010\, he was a professor in Fudan University\, China. From 2006-2010\, he was a professor and chair in Department of Biomedical Instrumentation\, School of Biomedical Engineering\, Shanghai Jiao Tong University\, China. \nCurrently\, he is a professor at Department of Biomedical Engineering\, Peking University. Dr. Wei is an SPIE Fellow\, and recipient of Chinese Outstanding Young Scholar Award. He has published more than 120 peer-reviewed papers\, including in Nature and PNAS. His research interests include cancer detection by optical means\, optical manipulation of cells\, and light treatment of Alzheimer disease. \n  \nREGISTER HERE FOR ZOOM \n  \nClick here to register for in-person attendance (lunch will be served) \n 
URL:https://bli.uci.edu/event/xunbin-wei/
LOCATION:BLI Library
CATEGORIES:2023 Virtual Seminar Series,LAMP Seminar
ATTACH;FMTTYPE=image/png:https://bli.uci.edu/wp-content/uploads/2025/03/Screenshot-2025-03-25-141956.png
END:VEVENT
END:VCALENDAR