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SUMMARY:Gultekin Gulsen\, Ph.D.
DESCRIPTION:True multi-modality optical molecular imaging – where both modalities interact and work in harmony. \nAbstract  \nThe main goal of the molecular imaging community has been achieving higher resolution and better quantitative accuracy.\nFor nearly two decades\, I have been spending effort for the same purpose\, mainly integrating optical imaging with anatomic\nimaging modalities such as MRI and X-ray CT. For example\, my team has developed a gantry-based combined X-ray CT and\nFluorescence Tomography system for small animal imaging. This system is unique in that both X-ray CT and optical imaging\nsystems are on the same gantry rotating around the animal and capable of revealing cross-sectional background optical\nabsorption map and anatomic images that can be used to obtain quantitatively correct fluorophore concentration maps.\nAnother hybrid system that is being developed in my lab is a combined MRI-Diffuse Optical Tomography scanner for small\nanimal imaging in both absorbance & fluorescence modes. \nIn all of these applications\, optical and anatomic imaging modalities worked in harmony but independent from each other.\nRecently\, we have focused on development of novel multimodality techniques\, in which optical and anatomic imaging\nmodalities work in harmony and interact with each other to provide images that cannot be obtained solely with one or the\nother. This talk will highlight two of these true-multimodality imaging techniques developed in our lab: Photo-magnetic\nImaging (PMI) and Temperature Modulated Fluorescence Tomography (TM-FT)\, where optical tomography is achieved at MRI\nand Focused Ultrasound resolution\, respectively while preserving its superior sensitivity. \n  \nBiography \nDr. Gulsen is an Associate Professor in the Departments of Radiological Sciences\, Biomedical Engineering\, Physics & Astronomy\, and Electrical Engineering & Computer Science at the University of California\, Irvine. He has been serving as the Director of In vivo Functional Onco-Imaging Shared Resource of the UCI Cancer Center for more than15 years. His research involves development of both cutting-edge instrumentation and novel mathematical algorithms for multi-modality imaging techniques. Although most of those techniques have been related to optical molecular tomography\, his team was also involved in development of the the world’s first MR compatible SPECT small animal imaging and Positron Emission\nMammography systems. \n  \n 
URL:https://bli.uci.edu/event/gultekin-gulsen-phd/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://bli.uci.edu/wp-content/uploads/2023/01/Gultekin-UCI-best-pic.jpg
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