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X-WR-CALDESC:Events for Beckman Laser Institute
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BEGIN:VEVENT
DTSTART;TZID=UTC:20190603T120000
DTEND;TZID=UTC:20190603T130000
DTSTAMP:20190603T232041Z
CREATED:20190530T222905Z
LAST-MODIFIED:20190603T232041Z
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SUMMARY:Xueding Wang\, Ph.D.
DESCRIPTION:Department of Biomedical Engineering\nDepartment of Radiology\nUniversity of Michigan School of Medicine \nLight plus Sound: Photoacoustic Imaging and Treatment\nAbstract\nPhotoacoustic imaging (PAI)\, also referred to as optoacoustic imaging\, is an emerging biomedical imaging technology that is noninvasive\, nonionizing\, with high sensitivity\, satisfactory imaging depth and good temporal and spatial resolution. Like conventional optical imaging\, PAI presents the optical contrast which is highly sensitive to molecular conformation and biochemical contents of tissues and can aid in describing tissue metabolic and hemodynamic changes. Unlike conventional optical imaging\, the spatial resolution of PAI is not limited by the strong light diffusion but instead determined by the measurement of light-generated ultrasonic signals. As a result\, the resolution of PAI is parallel to high-frequency ultrasonography. \nAt the University of Michigan School of Medicine\, our research has been focused on clinical applications of PAI\, including arthritis\, cancer\, liver conditions\, Crohn’s disease\, and eye diseases.  In this talk\, I will introduce some of our recently development of PAI technologies\, including 1) development of point-of-care PAI system for human inflammatory arthritis\, and 2) development of quantitative PAI for evaluating histological microfeatures and microenvironment of cancer. I will also present our recent development of a photoacoustic based anti-vascular technology named photo-mediated ultrasound therapy (PUT). Using a combination of a low intensity laser concurrently with ultrasound\, PUT can noninvasively remove microvessels without damaging surrounding biological tissue\, and shows potential to the treatment of a variety of diseases associated with neoangiogenesis\, such as age-related macular degeneration and diabetic retinopathy\, as well as port-wine stain and cancer. \nBiography\nDr. Xueding Wang is a Professor at the Department of Biomedical Engineering\, University of Michigan\, holding an adjunct Professor position at the Department of Radiology.  Before working as an independent principle investigator\, Dr. Wang received his Ph.D. from Dr. Lihong Wang’s lab at the Dwight Look College of Engineering at Texas A&M University\, and then finished postdoctoral training at the University of Michigan School of Medicine under the guidance of Prof. Paul Carson.  Dr. Wang has extensive experience in optical and ultrasound imaging and treatment system development and adaptation of novel diagnostic and therapeutic modalities to preclinical and clinical settings.  Sponsored by NIH\, NSF\, DoD and other funding agencies\, his research has led to over 110+ peer-reviewed publications.  At the University of Michigan Medical School\, a major part of his research is focused on clinical applications of photoacoustic imaging and therapy\, including those involving arthritis\, prostate cancer\, liver conditions\, breast cancer\, Crohn’s disease\, and eye conditions.  Dr. Wang is the recipient of the Sontag Foundation Fellow of the Arthritis National Research Foundation in 2005\, and the Distinguished Investigator Award of the Academy of Radiology Research in 2013. He is also sitting on the editorial boards of scientific journals including Photoacoustics\, Journal of Biomedical Optics\, Medical Physics\, and Ultrasonic Imaging\, and being the steering committee member of the Journal of Lightwave Technology. \nFor more information or to schedule a meeting with the speaker\, please contact Hanna Kim.\nHosted by Dr. Bernard Choi
URL:https://bli.uci.edu/event/xueding-wang-ph-d-2/
LOCATION:3201 Natural Sciences II
ATTACH;FMTTYPE=image/jpeg:https://bli.uci.edu/wp-content/uploads/2019/02/Wang-2.jpg
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BEGIN:VEVENT
DTSTART;TZID=UTC:20190606T123000
DTEND;TZID=UTC:20190606T133000
DTSTAMP:20190524T004017Z
CREATED:20190521T230028Z
LAST-MODIFIED:20190524T004017Z
UID:21481-1559824200-1559827800@bli.uci.edu
SUMMARY:Joseph A. Izatt\, PhD
DESCRIPTION:Michael J. Fitzpatrick Professor of Engineering in the Edmund T. Pratt School of Engineering\nProfessor of Ophthalmology\, and Program Director for Biophotonics at the Fitzpatrick Institute for Photonics at Duke University \nNew Optical Technologies for Real-Time Biomedical Imaging and Image-Guided Surgery\nAbstract\nCutting edge optical biomedical imaging technologies adaptively control optical wavefronts and exploit spatial and temporal coherence to obtain wavelength-scale measurements of structure and function inside living biological tissues\, while leveraging optical communications bandwidths to enable real-time 3D imaging. We have developed implementations of these technologies for multiple applications including super-resolved non-invasive retinal imaging\, flexible hand-held interactive clinical diagnostic imaging\, and real-time intrasurgical visualization and operative guidance. These advances allow for continuous volumetric microstructural imaging in living patients\, and extend the benefits of the latest imaging technologies to previously inaccessible patient populations. Using these tools\, we have demonstrated live imaging of individual retinal receptor cells both with and without adaptive optics\, including the first demonstrations of retinal cone cell imaging in infants and children. We have pioneered the integration of optical coherence tomography into ophthalmic microsurgery\, including surgical microscope-integrated image acquisition\, real-time augmented reality visualization\, and image-guided tele-operative and cooperative robotic manipulation of surgical tools with micrometer-scale precision. Several of these technologies have accomplished the transition from basic research\, to clinical trials\, to wide-scale adoption and commercial success\, and thus serve as useful examples of the accumulating impact and continuing importance of innovation in biomedical optics and biophotonics.  \nBiography\nJoseph A. Izatt is the Michael J. Fitzpatrick Professor of Engineering in the Edmund T. Pratt School of Engineering\, Professor of Ophthalmology\, and Program Director for Biophotonics at the Fitzpatrick Institute for Photonics at Duke University. Prof. Izatt’s research interests include biomedical optics and spectroscopy\, coherence-based and wavefront-optimized tomographic optical imaging\, and novel instrumentation for intrasurgical visualization and manipulation. He has authored over 200 peer-reviewed publications\, more than 350 contributed and 130 invited lectures and presentations\, and more than 70 issued patents\, which altogether have accumulated over 38\,000 citations. Izatt was the founding Editor-In-Chief of Biomedical Optics Express\, OSA’s principle outlet serving the biomedical optics community\, and has co-chaired the leading annual conference in Optical Coherence Tomography (at SPIE’s Photonics West) for two decades. Professor Izatt has worked with multiple companies to license commercial technologies related to optical biomedical imaging\, including co-founding Bioptigen\, Inc.\, which was acquired by Leica Microsystems in 2015. Dr. Izatt is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE)\, The International Society for Optics and Photonics (SPIE)\, The Optical Society (OSA)\, and the National Academy of Inventors (NAI). \nFor more information or to schedule a meeting with the speaker\, please contact Hanna Kim.\nHosted by Dr. Matt Brenner
URL:https://bli.uci.edu/event/joseph-a-izatt-phd/
LOCATION:BLI Library
ATTACH;FMTTYPE=image/jpeg:https://bli.uci.edu/wp-content/uploads/2019/05/Izatt.jpg
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BEGIN:VEVENT
DTSTART;TZID=UTC:20190610T120000
DTEND;TZID=UTC:20190610T130000
DTSTAMP:20190604T034800Z
CREATED:20190530T230819Z
LAST-MODIFIED:20190604T034800Z
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SUMMARY:Anita Mahadevan-Jansen\, PhD
DESCRIPTION:Professor of Biomedical Engineering at Vanderbilt University  \nProblem-based research shortens the pathway to to clinical translation of light-based technologies\nAbstract\nMedicine is a problem rich environment where there is a critical need for new solutions that ease the life of the patient\, the physician and the caregiving staff. For at least some of these problems\, biophotonics could well be the answer! Optical techniques can be used to provide real-time assessment for screening\, diagnosis\, monitoring and guidance of therapy. In this presentation – I will discuss 2-3 different medical challenges and the optical solution that was developed and implemented in a clinical setting. These examples include the application of near infrared fluorescence imaging for the anatomical detection of the parathyroid gland during endocrine surgery and in vivo biochemical characterization of the pregnant human cervix towards understanding preterm birth.  \nBiography\nDr. Mahadevan-Jansen translates optical techniques for clinical detection of tissue physiology and pathology. Her primary research at the Vanderbilt Biophotonics Center\, is to investigate the applications of optical spectroscopies and imaging for disease diagnosis and guidance of therapy. She received her bachelor’s and master’s degrees in Physics from the University of Bombay (Mumbai)\, India\, and a master’s and PhD degrees in Biomedical Engineering from the University of Texas at Austin. She joined the Vanderbilt engineering faculty in 1996. She is currently the Orrin H. Ingram Professor of Biomedical Engineering at Vanderbilt University and holds a secondary appointment in the Departments of Neurological Surgery and Otolaryngology. She is the founding Director of the Vanderbilt Biophotonics Center\, the Director of the Vanderbilt branch of the Center for Integration of Research in Teaching and Learning (CIRTL)\, an NSF funded 46-institution center as well as Director of Undergraduate Studies for the Department of Biomedical Engineering at Vanderbilt University.\nShe is currently on the Board of Directors of the International Society for Optical Engineering (SPIE) and is a fellow of SPIE\, Optical Society of America (OSA) as well as the American Institute of Medical and Biological Engineering (AIMBE). \nFor more information or to schedule a meeting with the speaker\, please contact Hanna Kim.\nHosted by Dr. Matt Brenner
URL:https://bli.uci.edu/event/anita-mahadevan-jansen-phd/
LOCATION:BLI Library
ATTACH;FMTTYPE=image/jpeg:https://bli.uci.edu/wp-content/uploads/2019/05/anita.jpg
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BEGIN:VEVENT
DTSTART;TZID=UTC:20190613T120000
DTEND;TZID=UTC:20190613T130000
DTSTAMP:20190603T231717Z
CREATED:20190603T230251Z
LAST-MODIFIED:20190603T231717Z
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SUMMARY:Anand Kumar\, PhD
DESCRIPTION:Assistant Professor\, Harvard Medical School\nAssistant Professor\, Massachusetts General Hospital\, Boston \nBiological imaging with time domain fluorescence\nAbstract\nMolecular imaging combines the use of disease targeted contrast agents with advanced imaging techniques to visualize disease processes in whole living organisms from the small animal to the human scale. Optical techniques are emerging as promising tools for molecular imaging by providing functional contrast\, and are particularly attractive given the spectral and fluorescence lifetime tunability of near infrared fluorophores. This allows the exciting possibility of multiplexing using fluorescence spectral and lifetime contrast. \nMy laboratory is focused on the development and application of whole-body time domain imaging techniques\, with emphasis on exploiting lifetime contrast for enhanced sensitivity and specificity of disease detection in vivo.  Although fluorescence lifetime imaging has been widely used in microscopy using fluorescence lifetime imaging (FLIM)\, the application of lifetime imaging for macroscopic subjects has been limited by several challenges.  This presentation will outline some of these challenges and how they can be addressed using theoretical and experimental methods for time domain imaging.  In particular\, I will discuss a novel algorithm for tomographic lifetime multiplexing which allows the complete separation and 3-D localization of multiple lifetimes simultaneously present within biological tissue. Recent extensions of this work to the spatial frequency domain using modulated sources will also be discussed. I will then present in vivo applications of the technology pertaining to cancer and cardiac disease models. I will finally discuss our recent progress towards clinical applications of fluorescence lifetime imaging for cancer detection. \nBiography\nAnand Kumar is an Assistant Professor at Harvard Medical School and the Massachusetts General Hospital in Boston.  Dr. Kumar received his M.Sc. from the Indian Institute of Technology\, Chennai\, India and Ph. D. from Northeastern University\, Boston\, both in Physics. Following his doctoral work on ultrafast laser spectroscopy\, he worked in Sycamore Networks as a Senior Optical Engineer for 2 years\, where he designed commercial fiber optic networks. Subsequently\, he moved to the Athinoula A. Martinos center in 2002 as a post-doctoral fellow and joined the faculty of the center as an Instructor in 2007 and Assistant Professor in 2012. His current research focus is on preclinical and clinical applications of diffuse optical tomography and optical molecular imaging\, with particular emphasis on time domain imaging techniques. \nFor more information or to schedule a meeting with the speaker\, please contact Hanna Kim.
URL:https://bli.uci.edu/event/anand-kumar-phd/
LOCATION:3201 Natural Sciences II
ATTACH;FMTTYPE=image/jpeg:https://bli.uci.edu/wp-content/uploads/2019/06/ANAND-KUMAR-192.jpg
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