From Optical to Optoacoustic Imaging: Technology Advances and Clinical Translation Abstract Biological discovery is a driving force of biomedical progress. With rapidly advancing technology to collect and analyze information from cells and tissues, we generate biomedical knowledge at rates never before attainable to science. Nevertheless, conversion of this knowledge to patient benefits remains a slow […]
Relativistic Compton Scattering Experiments: Applications to Science and Medicine Biography James Rosenzweig is a Distinguished Professor of Physics in the UCLA Department of Physics and Astronomy specializing in research into advances accelerator, beam and radiation techniques, and their frontier applications across science. In pursuit of these goals, he directs a large research group at UCLA, […]
Low-coherence Biophotonics Imaging for the Brain Abstract This talk will highlight our recent efforts in exploring the brain using low-coherence light. We will discuss two scenarios: intraoperative assessment of brain cancer infiltration in patients and real-time imaging of dynamic neural activities in freely behaving rodents. In the first scenario (clinical translation), we developed a color-coded […]
Pitfalls in Clinical Gastroenterology Abstract Gastroenterology is a multi-organ medical specialty pertaining to the treatment of the entire alimentary tract. I would like to introduce biomedical concepts and current treatment and diagnostic modalities of common gastrointestinal disorders and in turn discuss the current limitations of technological and clinical limitations to spark collaboration and ideas for […]
Controlling Light to Reimagine Clinical Diagnostics Abstract Current diagnostic testing faces several challenges, including limited multiplexing capabilities, a lack of quantitation information, the need for centralized laboratories, and/or cold chain custody. In this talk, we highlight the use of photonic resonators and plasmonic enhanced sensors as tools to address these critical gaps in diagnostics. Both […]
Distributed Charge Compton Sources and the Precision Detection and Treatment of Disease Abstract Medical robotics has been widely applied in areas such as surgical assistance, enabling higher precision, reduced fatigue, and enhanced performance, and tele-operation, allowing surgeons to perform procedures remotely without being physically present with the patient. A key enabler of medical robotics is […]
Small but mighty: Micropysiological models for simulating complex clinical oncology workflows Abstract Microphysiological tumor models (μPTMs) are tissue-engineered 3D tumors that are grown in the lab and retain the biological and functional characteristics of the tissue of origin. These μPTMs provide a powerful model of individual patients’ tumor and are used for drug discovery, cancer […]
Listening to the Sound of Light with A Robot: Fusion of Imaging and Robotics for Healthcare Abstract Medical robotics has been widely applied in areas such as surgical assistance, enabling higher precision, reduced fatigue, and enhanced performance, and tele-operation, allowing surgeons to perform procedures remotely without being physically present with the patient. A key enabler […]
Body-Interfaced Biosensors Abstract The rise of personalized medicine is reshaping traditional healthcare, enabling predictive analytics and tailored treatment strategies. In this talk, I will discuss our progress in developing wearable, implantable, and ingestible electrochemical biosensors for real-time molecular analysis. These bioelectronic systems autonomously access and sample diverse body fluids—including sweat, interstitial fluid, gastrointestinal fluid, wound […]
Single molecule fluorescence approaches reveal that DEAD-Box RNA helicases cluster in dynamic hubs for protein synthesis initiation Abstract DEAD-box helicases, DDX3 and eukaryotic initiation factor 4A (eIF4A), play essential roles in translation initiation, cytoplasmic surveillance for foreign RNAs and in facilitating cellular stress response. Using multi-parameter confocal fluorescence burst spectroscopy, we discovered that sex chromosome-encoded […]
