Michelle Khine

Professor, Biomedical Engineering
Professor, Materials Science and Engineering

Dr. Michelle Khine is a professor of Biomedical Engineering and Materials Science and Engineering at UC Irvine. She is Founding Director of Faculty Innovation at the Samueli School of Engineering and Founding Director of BioENGINE (BioEngineering Innovation and Entrepreneurship) at UC Irvine.

From 2006-2009 and prior to joining UC Irvine, Dr. Khine served as assistant and founding professor at UC Merced. At UC Merced, Shrink Nanotechnologies Inc., the first start-up company from the youngest UC campus, was spun-out of the research in the Khine Lab.

Michelle received her B.S. and M.S. from UC Berkeley in Mechanical Engineering and her Ph.D. in Bioengineering from UC Berkeley and UC San Francisco. In the Berkeley Sensor and Actuator Center under Professor Luke P. Lee, Ph.D., Khine developed microfabricated polymeric devices for cellular manipulation and analyses. As a Microsystems and Engineering Applications Institute Fellow, she also concurrently worked at Sandia National Laboratory. While in graduate school, she spun-out a company, Fluxion Biosciences (San Francisco), based on her dissertation work of single-cell electroporation.

Dr. Khine is the scientific founder of six start-up companies. She was the recipient of the TR35 Award, honored as one of Forbes “10 Revolutionaries” in 2009 and by Fast Company Magazine as one of the “100 Most Creative People in Business” in 2011. She was awarded the National Institutes of Health (NIH) New Innovator’s Award, was a finalist in the World Technology Awards for Materials and was named by Marie‐Claire magazine as, “Women on Top: Top Scientist.” She was the recipient of the Innovator of the Year 2017 for the Samueli School of Engineering at UC Irvine. Michelle is a Fellow of the American Institute of Medical and Biological Engineering (AIMBE), as well as a Fellow of the National Academy of Inventors.

Research Interests

+ Single Cell Electroporation

+ Shrinky-Dink Microfluidics

+ Microsystems for Stem Cell Differentiation

+ Canary on a Chip

+ Quantitative Single-Cell Analysis of Receptor Dynamics and Chemotactic Response on a Chip

  • Education

    B.S., Mechanical Engineering, UC Berkeley (1999)
    M.S., Mechanical Engineering, UC Berkeley (2001)
    Ph.D., Bioengineering, UC San Francisco and UC
    Berkeley (2005)

  • Phone

    949.824.4051