Advancing In-Vivo Human Brain Tissue Classification: A Multimodal Approach Integrating Machine Learning, Hyperspectral Imaging and Depth Information Abstract This talk will present a novel approach to classify in vivo human brain tissue in real time using a multimodal imaging technique that integrates hyperspectral imaging and depth information in a recently developed system called Slim Brain. […]
Hyperspectral Image and Video Processing in Neurosurgery: the HELICoiD, NEMESIS-3D-CM, and STRATUM Research Projects Abstract Brain tumor surgery is one of the most complex procedures that benefits from integrated digital diagnostics. Differentiating pathological tissue margins and interpreting multimodal data from a variety of independent devices are among the main challenges neurosurgeons face during brain tumor […]
Development of wearable laser speckle imaging devices for use at the point-of-care Abstract While laser speckle contrast imaging (LSCI) was historically confined to bulky benchtop systems, research teams have recently developed hand-held and wearable laser speckle systems. For these systems to be useful in a clinical setting, hand-held devices must be lightweight and compact enough […]
Toward High-Speed Light-Field Biophotonics Abstract Visualizing the diverse anatomical and functional traits within the densely packed cellular space and over large heterogeneous populations unfolds critical details of the fundamentals of living organisms. In this talk, I will present my laboratory’s recently developed advanced microscopy techniques for high-throughput extraction of molecular information in cells and tissues […]
Multimodal Metabolic Nanoscopy for Studying Aging and Related Diseases Abstract Understanding how metabolism functions in multicellular organisms is essential for revealing the fundamental mechanisms of numerous biological processes. Metabolism involves the creation, transformation, and breakdown of biomolecules, acting according to genetic instructions. Traditional imaging techniques like MRI, PET, fluorescence, and mass spectrometry come with limitations. […]
From Optical to Optoacoustic Imaging: Technology Advances and Clinical Translation Abstract Biological discovery is a driving force of biomedical progress. With rapidly advancing technology to collect and analyze information from cells and tissues, we generate biomedical knowledge at rates never before attainable to science. Nevertheless, conversion of this knowledge to patient benefits remains a slow […]
Relativistic Compton Scattering Experiments: Applications to Science and Medicine Biography James Rosenzweig is a Distinguished Professor of Physics in the UCLA Department of Physics and Astronomy specializing in research into advances accelerator, beam and radiation techniques, and their frontier applications across science. In pursuit of these goals, he directs a large research group at UCLA, […]
Low-coherence Biophotonics Imaging for the Brain Abstract This talk will highlight our recent efforts in exploring the brain using low-coherence light. We will discuss two scenarios: intraoperative assessment of brain cancer infiltration in patients and real-time imaging of dynamic neural activities in freely behaving rodents. In the first scenario (clinical translation), we developed a color-coded […]
Pitfalls in Clinical Gastroenterology Abstract Gastroenterology is a multi-organ medical specialty pertaining to the treatment of the entire alimentary tract. I would like to introduce biomedical concepts and current treatment and diagnostic modalities of common gastrointestinal disorders and in turn discuss the current limitations of technological and clinical limitations to spark collaboration and ideas for […]
Controlling Light to Reimagine Clinical Diagnostics Abstract Current diagnostic testing faces several challenges, including limited multiplexing capabilities, a lack of quantitation information, the need for centralized laboratories, and/or cold chain custody. In this talk, we highlight the use of photonic resonators and plasmonic enhanced sensors as tools to address these critical gaps in diagnostics. Both […]
